take one healthy diet during breastfeeding manages to normalize the lipid content in milk and Prevent metabolic disturbances in offspring, These are data from a study by the Center for Biomedical Research in Network (CIBEROBN) in the obesity and nutrition sector. The research is published in Molecular Nutrition and Food Research.
Through this study, we sought Evaluate in an animal model if normalizing maternal diet during lactation can prevent harmful effects that result from consumption of an obesogenic diet They act on the ‘lipidome’ or lipidomic profile (the set of hundreds of lipids) in breast milk and offspring plasma before and during pregnancy, which suggests it is possible to achieve this.
reverse pregnancy damage
These new insights are relevant because they show that Resuming a healthy maternal diet during breastfeeding can prevent, at least in part, Metabolic disorders caused by poor diet and obesity during the prenatal stages,
Furthermore, previous intervention studies in animal models have shown that consumption of an obesogenic diet during the perinatal period affects mammary gland function and, therefore, milk composition. This means that these changes can “program the offspring” to have a greater tendency to develop chronic deformities in adulthood.
Intervention during breastfeeding
With this in mind, the researchers considered it “interesting” to study potential intervention strategies during the breastfeeding period to prevent adverse effects caused by an unbalanced maternal diet during or even before pregnancy.
To do this, he did a Lipidomic Profile Analysis To determine changes in the said profile that could potentially be associated with the offspring’s risk of developing diseases at later stages of life. They also analyzed the plasma lipid profiles of puppies in the late stages of lactation.
The results of this study showed that maternal consumption of an obesogenic diet during the perinatal period (specifically, one month before pregnancy and during pregnancy and lactation) was associated with a marked change in the lipid composition of the milk and the plasma of their babies. causes. preliminary stage.
Such changes were largely reversed in the milk of mothers who had received a standard (balanced) diet during lactation, and in the plasma of their offspring. The reversal of these changes is related, at least in part, to the restoration of expression levels. Adiponectin hormone in the mammary gland. aas well as decreased expression of several proinflammatory factors.
Extrapolation to Humans
The authors of the research, led by Professor Catalina Pico, are now studying the extent to which these results can be extrapolated to humans.
In any case, they recommend extreme caution in feeding during lactation. This is “a critical period” in which it is possible to correct metabolic changes in offspring that may have been poorly programmed from a previous period of unhealthy eating or lifestyle.