a study led by Higher Council for Scientific Research (CSIC)and published in ‘Frontiers in Cell and Developmental Biology’, have shown the effectiveness of Tultrasound therapy In inhibition of cancer cells in cases of pancreatic cancer, which opens the door for the development of new non-invasive treatments based on ultrasonic technology to paralyze the growth of solid tumors.
The process of spread and migration of cancer cells with the development of solid tumors and current treatments involve ionizing radiation They destroy both malignant and healthy cells.
“Our research raises the possibility of developing a new therapy based on ultrasonic, non-ionizing technology for the first time, which would mean a non invasive treatmentLow cost, easy to implement and without collateral damage for patients”, elaborated CSIC researcher at the ‘Leonardo Torres Quevedo’ Institute of Physical and Information Technologies (ITEFI), Iciar Gonzalez.
Specifically, the researchers developed the research in vitro samples Pancreatic cancer. “We applied only twenty minutes of low-intensity ultrasound doses to a sample of pancreatic cancer cells PANC-1 and We managed to stop collective and individual progress of cells in a monolayer for at least two days”, argued the expert.
Application of ultrasonic waves in some acoustic situations for 15 or 20 minutes Inhibits the ability of cell movement for a long time, more than 48 hours or even up to 3 days after treatment. In addition, the scientists also observed some disruptions in cell proliferation processes that we are currently analyzing in other experiments in our laboratories.
The next step will be in vivo testing with mice to demonstrate the efficacy and suitability of this therapy. the purpose is test with mice Good results were obtained ‘in vitro’ with a variety of tumours. The experiments with mice will be carried out in collaboration with researchers from Harvard University, the University of the Basque Country and the Ramon y Cajal Institute for Health Research, thanks to the use of a small ultrasonic device adjustable for each animal.