Jewish link – Israeli scientists suggest discovering fungi in the human body may provide a new way to detect cancer early The Times of Israel,
In collaboration with American colleagues, they examined tumors from 17,000 cancer patients to document the fungus present in the tissue for the first time.
Until now, research on fungi in tumors was very limited, and scientists considered their presence to be rare. “We were surprised to find that, in fact, it is more common to find tumors with fungi than without them,” says Doctor. Ilana Livyatanof Weizmann Institute of Science,
His team created an innovative “map” dedicated to the topic, and claims it can be used to create new detection methods.
Since d n The fungus can be detected in the blood, with scientists hoping that doctors may one day use a blood test to detect cancer.
The “map” describes the characteristic fungus of 35 different types of tumors, so these tests can go beyond just indicating the existence of cancer and indicating where in the body it can be found.
“This could offer a new way of diagnosing cancer through a simple blood test that detects fungi in tumors,” he explained. Livyatan,
“And beyond diagnosis, it could really revolutionize tumor research. It’s one of those eye-opening moments that forces us to reevaluate our assumptions about cancer, because fungi are no longer tumors.” represents a new idea in analysis.”
This study published in the journal roomis the result of collaboration between Weizmann Institute of Science And this University of California San Diego School of Medicine, Tel-Aviv University And this sheba medical center Also contributed to research.
In recent years, scientists have observed that tumors harbor large populations of microbes. Many important studies have been done, one of which weismanOn bacterial patterns in malignant tumors.
team of Weisman-California states that in addition to opening up a new avenue for cancer detection, their findings suggest that studying fungi in patients provides information that could shape prognosis and treatment plans.
Scientists found several links between fungi and their chances of survival. For example, when tumors from breast cancer patients contain a specific fungus – Malassezia globosa, which is naturally found on the skin – it correlates with better chances of survival.
They also identified specific fungi in the patients. melanomaThey are found in greater numbers in people who respond well to immunotherapy.
Teacher yitzhak puppiesof Institute WeizmannHopefully, in the years to come, scientists will delve deeper into the relationship between fungi and cancer and explore how the findings can be used to influence treatment. “This study sheds new light on the complex biological environment of tumors, and future research will reveal how fungi affect cancer development,” he said.
his colleague, professor Ravid Straussmannoted that the new study suggests that fungal activity is “a new and emerging hallmark of cancer.”
“These findings should prompt us to explore the potential effects of tumor fungi and to re-evaluate almost everything about cancer through the lens of the microbiome,” he said.