After more than forty years of research, the scientific community, led by eminent geneticist and molecular biologist Miroslav Radman and Naos (a French multinational company that integrates the dermatological brands Bioderma, Asthederm and Etat Pur), Finds one of the most promising processes that explains why skin aging occurs, “Skin ages because its cells age and cells age because their proteome (all the proteins that make up an organism) oxidizes.”
cell aging chemistry, which includes the skin, involves the oxidation of proteins. With the passage of time, these structures are subject to various changes and carbonylation becomes their biggest threat. Carbonylated proteins lose their three-dimensional structure and are no longer able to perform their vital functions, so they must be recycled and disposed of so that they do not become toxic compounds. However, with age they become more difficult to eliminate and they leave their mark on the skin in the form of wrinkles, loss of shine, firmness and density.
,The survival of the organism depends on the activity of its proteins., Same goes for aging you. If we act on the changes of the proteome, which are the root cause of chemical ageing, it is possible to intervene simultaneously on each of its consequences”, explains Rademann.
Redman, on understanding the key to a long and healthy life Focuses on extremophile bacteria, These long-lived organisms are able to survive and thrive in extreme levels of radiation, temperature or aridity thanks to their perfectly conserved proteomes. But thirteen years ago the paradigm changed, when research teams at Naos, inspired by Professor Redman’s work, selected an extremophile bacterium (Arthrobacter agilis) indigenous to Antarctica, which had stronger antioxidants than the reference bacteria used by the teacher. There were qualities.
this bacteria Provides best possible protection to skin cells due to the presence of red pigments Those that mimic the skin’s natural defense systems: Bacteria ruberin. From its extraction, Naos Laboratories has created the Edge Proteome Biotechnological Patent. This revolutionary approach, the result of a collaboration with the Mediterranean Institute for Life Sciences (Medils), founded by Radman himself, reduces levels of carbonylated proteins, prevents irreversible damage and helps restore optimal cell and tissue function.
with more than 80% protection efficiency, This active ingredient forms a physical shell that protects the structure of the proteins and allows them to remain active for longer periods of time. But this data is not the only one it yields, as it also shows an antioxidant power better than that of other reference molecules. “This marks the beginning of a new generation of ‘healthy ageing’ skin care products aimed at permanently preserving health and homeostasis,” the company says.
“Due to their dual mechanism of action, these molecules, the result of billions of years of evolution, prevent irreversible damage to the skin’s proteome and make it possible to restore improved cellular and tissue functionality in the long term. This new approach constitutes first-rate protection against skin aging: By intervening at an earlier stage of the mechanisms involved in cell longevity, the beneficial effects appear later in all signs of ageing”, concluded Isabelle Benoit, member of the NAOS Scientific Committee.
