The Royal National Academy of Medicine wants to honor research on aging by rewarding two pioneers of this new field that promises to revolutionize something that was hitherto considered inevitable: the slow degradation of the body until death.
In a ceremony to be held this Thursday, September 22, the corporation chaired by oncologists Eduardo Diaz Rubio will appoint an honorary academician Shinya YamanakaWinner of the 2012 Nobel Prize in Physiology and Medicine (along with British John Gurdon) for the discovery of induced pluripotent stem cells, which can be reprogrammed to grow as part of any tissue in the body.
The Academy will also honor the Albacete researcher with a Medal of Honor Juan Carlos IspisuaDirector of Altos Labs Institute of Sciences in San Diego (United States), a private institution specializing in research to reverse aging.
[Juan Carlos Izpisúa: “Rejuvenecer las células ayudará a retrasar la aparición del cáncer”]
Among his achievements, Izpisa discovered a class of RNAs that accumulate in the nucleus of cells of people with Progeria, a disease that causes premature aging of the body. Blocking this RNA has been shown to help reverse the symptoms of the disease in mice, prolonging their lives.
Izpissa and Yamanaka’s careers have crossed paths on several occasions. The last time was this year, when the Spaniard managed to reverse the aging of middle-aged and elderly mice by partially restoring cells to more youthful states.
They did this precisely by using four molecules (Oct4, Sox2, Klf4 and cMyc), the so-called ‘Yamanaka factors’ discovered by a Japanese scientist, that restore the epigenetic markers of DNA to their original pattern.
[Altos, el Laboratorio Secreto Que Ficha Premios Nobel para Lograr Que Con 50 Años Tengas 30]
These markers, which are added over time, are not part of the genome, but they affect and modify it. Playing an essential role in the aging of the body and the loss of its associated functions,
The Royal Academy of Medicine has decided to award Izpisa, born in the city of Helin in 1960, with a Medal of Honor for his “scientific, academic and health work”, in addition to his “great and important support to this Royal Academy”. . , On previous occasions, the award was given to relevant scientists such as Francisco Ayala (2016) and Francisco Martínez Mojica (2017).
As for Yamanaka, he will be awarded the rank of Honorary Academician for his “relevant scientific merits”, as indicated in the minutes of the Academy’s Governing Board held on June 14.