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Friday, January 27, 2023

Spain will end surveillance of hepatitis of unknown origin in children.

Ministry of Health told that “No more routine surveillance of hepatitis of unknown origin in children“, since, in Spain “no common cause has been found, nor has a greater increase been seen than expected”; although they clarify that “the research field will continue to study the related etiology”.

“In Spain, from the 17th week of 2022, Trends remain stable with no growth Nor have any other relevant events been detected in the United Kingdom in relation to this alert,” they emphasize.

This is reflected in the latest data report on the disease in Spain, where it is detailed that, h61 cases have been detected in this country as of December 23, 2022In the investigation of hepatitis of unknown origin in children, which means two more cases than those recorded in the previous report (59), which was issued on 14 November.

By CCAA, 4 cases have been detected in Andalusia; 1 in Aragon, 8 in the Balearic Islands (there were 7 in November); 2 in the Valencian Community; 1 in the Canary Islands; 3 in Castilla y León; 3 in Castile-La Macha; 9 in Catalonia; 6 in Galicia; 18 in Madrid; 5 in Murcia (there were 4 in November) and 1 in the Basque Country.

Of the 61, 49 are 10 years or less. The mean age of the cases under investigation was 5.4 years. (standard deviation 5.0 years) and the mean age was 4 years (range 0 months–16 years). By gender, 36 cases were girls (59%) and 25 were boys (41%), with a higher proportion of girls, especially in the 0 to 5 year group.

No cases with an epidemiological link have been detected. And the cases under investigation are residents of 12 CCAAs. As stated both in this report and in November, Three cases were transplanted, two of them died after transplant, While the third transplanted patient had a favorable development. In addition, there was a third death that had not been transplanted.

Microbiological and metagenomic investigations have been carried out in autonomous communities and the National Center for Microbiology and revealed 11 positive cases for herpes virus and Of the 42 analyzed, 18 (42.8%) were positive for adenovirus.

main cause hypothesis revolves around adenovirus infection, Associated with cases in the United Kingdom in a very significant way and a significant percentage of cases detected in the rest of the world.

In cases where information about symptoms is available, the most commonly reported were: Vomiting (35 cases; 60% of those with knowledge of this symptom), discomfort (34 cases; 65%), Fever (33 cases; 60%), Jaundice (26 cases; 48%) and stomach ache (26 cases; 46%). was notified diarrhea In 18 cases (33%), respiratory symptoms in 17 cases (32%) and rash in 11 cases (22%).

On April 5, 2022, the United Kingdom issued an alert to the World Health Organization after 10 cases of severe acute hepatitis of unknown cause were detected in children. In Spain, monitoring of this unit began from that moment on. By 24 November, 572 cases had been reported in 22 countries in Europe.Of which 280 are from the UK. Of the 320 cases for which this information is available, 24 (7.5%) received a liver transplant.

World Nation News Desk
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