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Wednesday, December 07, 2022

They find that women, and especially younger women, have a higher risk of diabetes after undergoing a hysterectomy.

They find that women, and especially younger women, have a higher risk of diabetes after undergoing a hysterectomy.

las women and especially people under the age of 45, who have gone through a Uterus They may be at increased risk of developing diabetes, according to a study of more than 83,000 middle-aged French women presented at the U.S. annual meeting. European Association for the Study of Diabetes (EASD) in this year Stockholm, Sweden),

Uterus may be recommended as a treatment for heavy periods loss of fibroids endometriosis And this gynecological cancer And it’s a surgery that removes the uterus, sometimes along with the fallopian tubes, ovaries, or cervix.

Previous studies in the same French cohort reported that Uterus is associated with an increased risk of arterial hypertension and heart disease the strokes, especially when accompanied by the removal of the ovaries; But to date few studies have examined the relationship between Uterus and risk of diabetes.

Moreover, most of them are related women. menopause And they didn’t take into account the potential effect of diet and physical activity.

To delve into this question, the researchers followed 83,582 women, with an average age of 51 years and 45 to 60 years old at the time of inclusion, who did not have diabetes at the start of the study.

Researchers analyzed data collected every two years using a questionnaire that addressed lifestyle-related factors, such as physical activity, eating habits, body mass index, smoking, menstrual age, Menopausal status, age of menopause and use of oral contraceptives. with a medical diagnosis of diabetes; Testing whether an unhealthy lifestyle affected the risk of diabetes in women who Uterus,

As a result, during an average follow-up of 16 years, 17,141 women reported a Uterus Of whom 2,672 developed diabetes.

Compared to women who did not have a hysterectomy, they were 27% more likely to develop diabetes, after adjusting for factors affecting the outcome, such as educational level, smoking, and family history of diabetes.

This relationship did not change significantly after additional adjustments for reproductive factors, such as age at menarche, menopausal status, or hormonal treatment; While there was no change in the relationship between diet quality and physical activity level Uterus And this diabetes Accident.

In addition, the authors found no association between being overweight and an increased risk of diabetes; And interestingly, the results suggested that a Uterus With ovaries still intact was associated with a 13% increased risk of diabetes, compared to a 26% increased risk after hysterectomy and oophorectomy, that is, removal of one or both ovaries.

According to the lead author of this work, Prof. fabric bonnet of René University and of Research Center in Epidemiology and Population Health, France, Results from this large French group, which was followed for an average of 16 years, showed that women who had a hysterectomy before the age of 45 had a 52 percent increased risk of developing type 2 diabetes.“and added that”Importantly, this risk of diabetes is higher when both ovaries are removed, but this increased risk persists even when both ovaries are preserved, and cannot be explained by unhealthy diet or physical inactivity.,

fact that in women who have a Uterus Before the age of 45, the overall risk of diabetes was 52% higher in people who did not have this surgery than those in this age group; Whereas women who had a hysterectomy after age 45 did not have a statistically significant increased risk.

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