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Friday, February 3, 2023

Vaccine against covid: they rush the national bivalent while the imported vaccine does not arrive

Unlike other countries in the region, Argentina has not yet reported about bivalent vaccine against covid, This is the formula against which some countries of the world are already in force of variants: ancestor of Wuhan and last known so far, omicron,

The labs that market them are Moderna and Pfizer, whose new versions have been approved by several health agencies in Europe and the United States, as well as in South America. ANMAT is not currently issued in Argentina.

local scene emerges out of regional Not only because of that pending bureaucratic aspect, but also for another important reason: Argentina will be relatively close to being able to vaccinate its population. The bivalent vaccine is made entirely in Argentina,

This is the ARVAC Cecilia Grierson, the first phase of which showed very good results and in the next few days step 2/3, The horizon of the researchers is that the test results can be presented in ANMAT april and may for its registration and, thus, has enabled it to use in june,

“We are on with the regulatory formalities and we hope that ANMAT authorizes us for phase 2/3 trials this month,” he said in the last hours Bugle One Kasara Source, a laboratory that has linked Conset with the National University of San Martín and other institutions for the project.

Part Of The Team Of Scientists Working With The Argentine Vaccine.  Photo: Andres De Elia

Part of the team of scientists working with the Argentine vaccine. Photo: Andres de Elia

When presenting the Phase 1 results, the researchers highlighted that the neutralizing antibodies generated by this booster (still in its first monovalent version) were senior officers For the reinforcement of Pfizer: Growth of 30 times against seven,

would be another advantage cost of thisEstimated cost between : 12 and 15 dollars per dose, while the imported bivalent oscillates between 26 and 30 dollars, At 2.5 million monthly bivalent doses (Cassará’s operational capacity), the country could save some $36 million every 30 days, The state will also pay in pesos.

The third advantageous element highlighted by local scientists is that the formula of this vaccine may be due to the features of its technological platform. modify quickly if required. So if Omicron were to be superseded by another major version, the change would come without delay.

It is not entirely clear whether the government will decide expect ARVAC vaccine results with the expectation that it may actually be available in the short term or in the meantime will achieve a lot of imported bivalent vaccines.

The vaccines that are in stock in the provinces today – about 7 million doses – work to protect against serious illness and death, but they are now almost no barrier against contagion. The sixth wave suggests that there has been a spurt in cases reported in the last 15 days From 3 thousand weekly to 27 thousand, He multiplied by nine. And that figure counts only a tiny fraction of the reality: the people who get tested.

With The Rise In Cases, The Demand For Vaccines Skyrocketed.  Photo: Ap

With the rise in cases, the demand for vaccines skyrocketed. Photo: Associated Press

Officials have already warned about the importance of implementing reinforcements in the current epidemiological context, although the warnings appear to be behind the curve, as al The period that always requires the development of immunity after application.

There has been a strong increase in the demand for doses against Covid. In the past week, the daily average number of vaccinations implemented was 61.167When in his recent apartment (when it seemed like the pandemic virus was a thing of the past) he collapsed below 14 thousand,

will be sufficient for the stock available at the new rate about three months, Then again, it is likely that eventually the promising results of the Cecilia Grierson vaccine for the seventh wave will already become a reality, with Argentina becoming one of the few countries in the world that has sanitary sovereignty against Covid.

trick, however, can be somewhat risky, A possible option would be to have a temporary back up of doses from Moderna or Pfizer. The country has already experienced “putting all eggs in one basket” at the start of the vaccination campaign, when it opted for AstraZeneca.

In that instance, the delay was caused precisely by problems final stage of investigation And, although active principle was subsequently produced in Argentina in due time and form, there were delays in packaging and formulation in Mexico that forced Argentina to they were well immunized In the first half of 2021.

The First 843,600 Doses Of Astrazeneca Arrived On May 24, 2021.  The Original Plan Was That 10 Million Would Have Arrived By That Time.

The first 843,600 doses of AstraZeneca arrived on May 24, 2021. The original plan was that 10 million would have arrived by that time.

The story is known. In an emergency, Argentina had to go out and buy Sputnik V from Russia. But that bet also had complications due to production difficulties of Component 2. That second hole was covered by Sinopharm, one of the least potent vaccines on the market.

All this happened in the context of postponing the contract with Pfizer. Finally, the vaccines with messenger RNA technology, which Argentina bought Seven months after approved by ANMATDominated the global immunity map.

Today the country has a balance of modern (first generation) vaccines, which are being used to introduce delayed boosters. There are those who doubt whether to apply the fifth dose or wait for the bivalent, but experts recommend taking the available vaccine if they run out. Four months since the last injection.

What the divalent will provide is more power against Omicron and therefore, is likely to reduce the circulation of the virus again, This would restore the nature of vaccines, which is to achieve herd immunity, rather than relegating them to an important but limited role as an individual shield against the development of infection.

Sources at the Casara laboratory said the original idea was for the Argentine vaccine to be prepared first, but along the way they decided that the development—in theory designed only against the gamma variant—would accommodate divalent form With the addition of Omicron as the target of the attack.

to get time, lab yes produce To keep them “at risk” while the health agency moves forward. The question that remains is whether this stock will, in time, be added to foreign rivals arriving in the country first, or will it only be when Argentines taste the honey of the recharged formula.


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